Focus on the processing of sensitive materials
The supercritical CO2 extraction and other processes based on CO2 as a solvent are of high interest for different areas of the pharmaceutical industry. This is mainly due to the unique properties of CO2, which allow the extraction of sensitive substances selectively and gently. Natex is experienced in providing everyone access to these special properties and provides the biggest and most advanced equipment in the pharmaceutical industry, regularly setting and expanding the cGMP standard for this high-pressure industry.
Clean, Standardized, and Repeatable
The extraction can take place at moderate temperatures, and the CO2 vaporizes without any residue in ambient conditions. This enables the production of high-quality pharmaceutical substances without any residues. It also offers potential for reducing process steps considerably, cleaning from impurities, and increasing the bioavailability of drugs. The gentle nature of supercritical CO2 extraction ensures that the integrity of sensitive compounds is maintained, making it an ideal method for producing high-purity pharmaceutical products.
Industrial Applications and Developments
Supercritical CO2 extraction is versatile and can be applied to various industrial processes within the pharmaceutical sector. Some of the key applications include:

Fulfilling All Required Regulations and Requirements
Pharmaceutical applications require the highest degree of repeatable processing, cleaning, safety, and traceability. NATEX plants fulfill customer-specific requirements in accordance with regulatory organizations such as the European Medicines Agency (EMA), the US Food and Drug Administration (FDA), the Medicines and Healthcare products Regulatory Agency (MHRA), and others. Compliance with these regulations ensures that the extraction processes meet the highest standards of quality and safety.
World-Leading Partner
NATEX’s position as an established supplier for the pharmaceutical industry is continuously manifested through raising the bar for cGMP in high-pressure applications. To fulfill the special requirements and validated cleaning possibilities, we have been developing unique, hygienic solutions for each part of the plant. This is why we work closely with selected suppliers to ensure ongoing improvement. Our commitment to innovation and quality makes us a trusted partner for pharmaceutical companies worldwide.